e-book Pseudomonas [Vol 4] - Molecular Biology of Emerging Issues

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Pseudomonas volume 4 is intended to collect some of the most relevant new emerging issues in the field of Pseudomonas that were not assembled in the three previous volumes. This fourth volume covers the following topics: - Virulence and Pathogens - Genomics and Proteomics - Physiology, Metabolism and Biotechnology Pseudomonas volume 4 will be of use to researchers working on these bacteria, particularly those studying virulence, genomics, physiology, biotechnology, etc.

Whitchurch, Monash University, Victoria, Australia. See All Customer Reviews. Shop Textbooks. Add to Wishlist. USD Greater understanding of chronic P. In vitro models can be used to address this need preliminarily, but mechanisms of evasion need to be tested in vivo. Additional novel approaches to studying chronic animal infection are nonetheless warranted; perhaps, models achieving bacterial persistence but not restricted to airway infection would be promising.

Regardless of the specific modeling, interpretation of data from diverse models will ultimately aid in deciphering the complexity of biofilm infections in human disease. For P. Pseudomonas biofilm matrix components in addition to the ones described here will likely continue to be revealed and add to the abundant diverse nature of biofilm matrix. The theme of diversity in function and survivability is hardwired into Pseudomonas spp. Matthew Byrd generated the image used in Fig. Special thanks to P. Oxford University Press is a department of the University of Oxford.

It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account. Sign In. Advanced Search. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents. Capsular polysaccharides.

Capsular polysaccharides: alginate. Capsular polysaccharides: levan. Aggregative polysaccharides. Aggregative polysaccharides: Psl. Aggregative polysaccharides: Pel. Aggregative polysaccharides: cellulose. Additional Pseudomonas biofilm matrix components. Polysaccharide-containing matrix components. Protein components of the biofilm matrix.

Conclusions and perspectives. Pseudomonas biofilm matrix composition and niche biology Ethan E. Oxford Academic.

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Google Scholar. Daniel J. Cite Citation. Permissions Icon Permissions. Abstract Biofilms are a predominant form of growth for bacteria in the environment and in the clinic.

Figure 1. Open in new tab Download slide. Figure 2. Figure 3. Figure 4. Figure 5. Search ADS. Pituitary stalk-section and some of its effects on endocrine function in the fetal lamb. Rhamnolipid-induced removal of lipopolysaccharide from Pseudomonas aeruginosa : effect on cell surface properties and interaction with hydrophobic substrates. Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes. High-frequency rugose exopolysaccharide production by Vibrio cholerae.

Putative virulence factors are released in association with membrane vesicles from Burkholderia cepacia. A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms. Role of antibiotic penetration limitation in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin. Antimicrobial activity of beta-lactam antibiotics against clinical pathogens after molecular inclusion in several cyclodextrins. A novel approach to bacterial resistance. Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms.

Nitric oxide signaling in Pseudomonas aeruginosa biofilms mediates phosphodiesterase activity, decreased cyclic di-GMP levels, and enhanced dispersal. Pyolipic acid. A metabolic product of Pseudomonas pyocyanea active against Mycobacterium tuberculosis. On a metabolic product of Ps. Structures of gram-negative cell walls and their derived membrane vesicles. Mucoid mutants of the biocontrol strain Pseudomonas fluorescens CHA0 show increased ability in biofilm formation on mycorrhizal and nonmycorrhizal carrot roots. Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients.

Influence of mucoid coating on clearance of Pseudomonas aeruginosa from lungs. Endogenous oxidative stress produces diversity and adaptability in biofilm communities. Rhamnolipids mediate detachment of Pseudomonas aeruginosa from biofilms. Pseudomonas aeruginosa uses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix. Dual regulation of mucoidy in Pseudomonas aeruginosa and sigma factor antagonism. Mucoid Pseudomonas aeruginosa in cystic fibrosis: characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection.

Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo. Murine models of acute and chronic lung infection with cystic fibrosis pathogens. Pseudomonas aeruginosa microevolution during cystic fibrosis lung infection establishes clones with adapted virulence. The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. Cariogenicity of Streptococcus mutans strains with defects in fructan metabolism assessed in a program-fed specific-pathogen-free rat model. The Pseudomonas aeruginosa exopolysaccharide Psl facilitates surface adherence and NF-kappaB activation in A cells.

Genetic and biochemical analyses of the Pseudomonas aeruginosa Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production. Direct evaluation of Pseudomonas aeruginosa biofilm mediators in a chronic infection model. Spontaneous release of lipopolysaccharide by Pseudomonas aeruginosa.

Alginate production by Pseudomonas putida creates a hydrated microenvironment and contributes to biofilm architecture and stress tolerance under water-limiting conditions. Role of LecA and LecB lectins in Pseudomonas aeruginosa -induced lung injury and effect of carbohydrate ligands. The Pel polysaccharide can serve a structural and protective role in the biofilm matrix of Pseudomonas aeruginosa.

The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix. Chemical analysis of cellular and extracellular carbohydrates of a biofilm-forming strain Pseudomonas aeruginosa PA Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants.

Rhamnolipid surfactant production affects biofilm architecture in Pseudomonas aeruginosa PAO1. A fatty acid messenger is responsible for inducing dispersion in microbial biofilms. De Kievit. Quorum-sensing genes in Pseudomonas aeruginosa biofilms: their role and expression patterns.

Biodegradation in a partially saturated sand matrix: compounding effects of water content, bacterial spatial distribution, and motility. The algR gene, which regulates mucoidy in Pseudomonas aeruginosa , belongs to a class of environmentally responsive genes. Mucoid-to-nonmucoid conversion in alginate-producing Pseudomonas aeruginosa often results from spontaneous mutations in algT , encoding a putative alternate sigma factor, and shows evidence for autoregulation.

The galactophilic lectin, LecA, contributes to biofilm development in Pseudomonas aeruginosa. Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation. Production and characterization of the slime polysaccharide of Pseudomonas aeruginosa. Regulation of alginate biosynthesis in Pseudomonas syringae pv. Comparison of the complete genome sequences of Pseudomonas syringae pv.

Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium. Biosynthesis of the Pseudomonas aeruginosa extracellular polysaccharides, alginate, Pel, and Psl. Two genetic loci produce distinct carbohydrate-rich structural components of the Pseudomonas aerguinosa biofilm matrix. Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms.

Genes encoding a cellulosic polymer contribute toward the ecological success of Pseudomonas fluorescens SBW25 on plant surfaces.

Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm

Surface expression of O-specific lipopolysaccharide in Escherichia coli requires the function of the TolA protein. Microscopic examination of natural sessile bacterial populations from an alpine stream. Identification of Tn 10 insertions in the rfaG , rfaP , and galU genes involved in lipopolysaccharide core biosynthesis that affect Escherichia col i adhesion.

The role of exopolysaccharides in Pseudomonas aeruginosa biofilm formation and architecture. The PprA—PprB two-component system activates CupE, the first non-archetypal Pseudomonas aeruginosa chaperone-usher pathway system assembling fimbriae. High-level beta-lactamase activity in sputum samples from cystic fibrosis patients during antipseudomonal treatment.

View Pseudomonas Vol 4 Molecular Biology Of Emerging Issues

Characterization of starvation-induced dispersion in Pseudomonas putida biofilms: genetic elements and molecular mechanisms. Increase in rhamnolipid synthesis under iron-limiting conditions influences surface motility and biofilm formation in Pseudomonas aeruginosa. Identification of an emergent and atypical Pseudomonas viridiflava lineage causing bacteriosis in plants of agronomic importance in a Spanish region.

Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Functional characterization of extracellular vesicles produced by Bacteroides gingivalis. Production of rhamnolipids by Pseudomonas chlororaphis , a nonpathogenic bacterium. Studies on the production of glycolipide by Pseudomonas aeruginosa. Purification and characterization of a cytotoxic exolipid of Burkholderia pseudomallei.

Small-colony variants of Pseudomonas aeruginosa in cystic fibrosis. Highly adherent small-colony variants of Pseudomonas aeruginosa in cystic fibrosis lung infection. Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function. A chemosensory system that regulates biofilm formation through modulation of cyclic diguanylate levels.

Transition from reversible to irreversible attachment during biofilm formation by Pseudomonas fluorescens WCS requires an ABC transporter and a large secreted protein. Adaptation of Pseudomonas aeruginosa during persistence in the cystic fibrosis lung. Form and function of biosurfactants for degradation of water-insoluble substrates.

Google Preview. Pseudomonas aeruginosa biofilm as a diffusion barrier to piperacillin. Production of mucoid exopolysaccharide during development of Pseudomonas aeruginosa biofilms. A chemically defined medium for slime production by coagulase-negative staphylococci. Pseudomonas aeruginosa post-transcriptional regulator RsmA represses biofilm extracellular polysaccharide Psl synthesis. Pseudomonas brassicacearum subsp. Identification of psl , a locus encoding a potential exopolysaccharide that is essential for Pseudomonas aeruginosa PAO1 biofilm formation.

Whole-genome sequence analysis of Pseudomonas syringae pv. Virulence factors are released from Pseudomonas aeruginosa in association with membrane vesicles during normal growth and exposure to gentamicin: a novel mechanism of enzyme secretion. Purification and characterization of a novel levanoctaose-producing levanase from Pseudomonas strain K Iron influences the expression of Helicobacter pylori outer membrane vesicle-associated virulence factors.

Alginate gene expression by Pseudomonas syringae pv. Aminoglycoside resistance of Pseudomonas aeruginosa biofilms modulated by extracellular polysaccharide. Copper as a signal for alginate synthesis in Pseudomonas syringae pv. Characterization of colony morphology variants isolated from Pseudomonas aeruginosa biofilms. Involvement of bacterial migration in the development of complex multicellular structures in Pseudomonas aeruginosa biofilms. Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants.

Swarming of Pseudomonas aeruginosa is dependent on cell-to-cell signaling and requires flagella and pili. Export of virulence genes and Shiga toxin by membrane vesicles of Escherichia coli OH7. Rhamnolipid of Pseudomonas aeruginosa in sputum of cystic fibrosis patients. A novel two-component system controls the expression of Pseudomonas aeruginosa fimbrial cup genes.

Production of mucoid microcolonies by Pseudomonas aeruginosa within infected lungs in cystic fibrosis.

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The global regulatory hns gene negatively affects adhesion to solid surfaces by anaerobically grown Escherichia coli by modulating expression of flagellar genes and lipopolysaccharide production. Differential lipopolysaccharide core capping leads to quantitative and correlated modifications of mechanical and structural properties in Pseudomonas aeruginosa biofilms. Contribution of alginate and levan production to biofilm formation by Pseudomonas syringae. Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. A cyclic-di-GMP receptor required for bacterial exopolysaccharide production.

Timing and localization of rhamnolipid synthesis gene expression in Pseudomonas aeruginosa biofilms. Characterization and mutational analysis of three allelic lsc genes encoding levansucrase in Pseudomonas syringae. Transient alginate gene expression by Pseudomonas putida biofilm residents under water-limiting conditions reflects adaptation to the local environment. Analysis of Pseudomonas aeruginosa conditional Psl variants reveals roles for the Psl polysaccharide in adhesion and maintaining biofilm structure postattachment.

Pseudomonas aeruginosa Psl is a galactose- and mannose-rich exopolysaccharide. Assembly and development of the Pseudomonas aeruginosa biofilm matrix. A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance. Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients. Membrane vesicles traffic signals and facilitate group activities in a prokaryote. Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.

Putative exopolysaccharide synthesis genes influence Pseudomonas aeruginosa biofilm development. Effects of Pseudomonas aeruginosa rhamnolipids on human monocyte-derived macrophages. Inhibition of macrophage phagocytosis by Pseudomonas aeruginosa rhamnolipids in vitro and in vivo. Surface-associated filamentous hemagglutinin induces autoagglutination of Bordetella pertussis.

Salmonella enterica serovar Typhimurium swarming mutants with altered biofilm-forming abilities: surfactin inhibits biofilm formation. Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization. The developmental model of microbial biofilms: ten years of a paradigm up for review. Phosphate-dependent modulation of c-di-GMP levels regulates Pseudomonas fluorescens Pf biofilm formation by controlling secretion of the adhesin LapA.

MutS deficiency and activity of the error-prone DNA polymerase IV are crucial for determining mucA as the main target for mucoid conversion in Pseudomonas aeruginosa. The roles of the quorum-sensing system in the release of extracellular DNA, lipopolysaccharide, and membrane vesicles from Pseudomonas aeruginosa.


Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT Significance of bacterial surface-active compounds in interaction of bacteria with interfaces. Cell-cell and cell-surface interactions mediated by cellulose and a novel exopolysaccharide contribute to Pseudomonas putida biofilm formation and fitness under water-limiting conditions.

Influence of putative exopolysaccharide genes on Pseudomonas putida KT biofilm stability. Role of alginate and its O acetylation in formation of Pseudomonas aeruginosa microcolonies and biofilms. Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development. Utilization of human respiratory secretions by mucoid Pseudomonas aeruginosa of cystic fibrosis origin. Effects of some organic pollutants on the exopolysaccharides EPSs produced by some Pseudomonas spp. Biosurfactant production in sugar beet molasses by some Pseudomonas spp.

Cell-free protein synthesis CFPS systems enable the production of protein without the use of living, intact cells. An emerging area of interest is to use CFPS systems to characterize individual elements for genetic programs [e. To enable this research area, robust CFPS systems must be developed from new chassis organisms. One such chassis is the Gram-negative Pseudomonas bacteria, which have been studied extensively for their diverse metabolism with promises in the field of bioremediation and biosynthesis.

Therefore, it is possible to prepare hundreds or even thousands of DNA templates without time-consuming cloning work. This opens the possibility to rapidly assess and validate genetic part performance in vitro before performing experiments in cells. To validate the P. Looking forward, our P. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

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